Early Human Development
Volume 51, Issue 3 , Pages 205-211, 10 July 1998

Carbonic anhydrase isoenzymes CAI and CAII in semen, decidua, chorionic villi and various fetal tissues

  • S Ali Akbar

      Affiliations

    • Molecular Biology and Biophysics Section, Biomedical Sciences Division, King's College London, Strand, London WC2 2LS, UK
    • Harris Birthright Research Centre for Fetal Medicine, Department of Obstetrics and Gynaecology, King's College Hospital, Denmark Hill, London, UK
    • Present address: Department of Biochemistry, Allama Iqbal Medical College, Lahore, Pakistan.
    • ,
  • K.H Nicolaides

      Affiliations

    • Harris Birthright Research Centre for Fetal Medicine, Department of Obstetrics and Gynaecology, King's College Hospital, Denmark Hill, London, UK
    • ,
  • P.R Brown

      Affiliations

    • Molecular Biology and Biophysics Section, Biomedical Sciences Division, King's College London, Strand, London WC2 2LS, UK
    • Corresponding Author InformationCorresponding author.

Received 7 July 1997; received in revised form 17 November 1997; accepted 18 November 1997.

Abstract 

ELISA methods were used to determine the concentrations of CAI and CAII in spermatozoa, seminal plasma, ovarian follicular fluid, decidual tissues, chorionic villi and various fetal tissues at 8–11 weeks gestation. Both CAI and CAII were expressed in all subjects except ovarian follicular fluid samples. The possible physiological role(s) of carbonic anhydrases in fertilization, implantation and fetal development are discussed.

Keywords:  CAI, CAII, Semen, Decidua, Chorionic villi, Fetal tissues

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PII: S0378-3782(97)00119-9

Early Human Development
Volume 51, Issue 3 , Pages 205-211, 10 July 1998

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