Early Human Development
Volume 83, Issue 1 , Pages 47-54 , January 2007

Salivary cortisol in preterm infants: Validation of a simple method for collecting saliva for cortisol determination

  • Madalynn Neu

      Affiliations

    • University of Colorado Denver and Health Sciences Center, School of Nursing, 4200 E. Ninth Avenue, Box C-288, Denver, CO 80262, United States
    • Corresponding Author InformationCorresponding author. Tel.: +1 303 315 1591; fax: +1 303 315 0907.
    • ,
  • Mark Goldstein

      Affiliations

    • University of Colorado Denver and Health Sciences Center, Department of Psychiatry, United States
    • ,
  • Dexiang Gao

      Affiliations

    • University of Colorado Denver and Health Sciences Center, Department of Pediatrics, United States
    • ,
  • Mark L. Laudenslager

      Affiliations

    • University of Colorado Denver and Health Sciences Center, Department of Psychiatry, United States

,Accepted 12 April 2006.

References 

  1. Laudenslager ML, Bettinger T, Sackett G. Saliva as a medium for assessing cortisol and other compounds in nonhuman primates: collection, assays, and examples. In:  Sackett G,  Ruppenthal G editor. Nursery rearing of nonhuman primates in the 21st century. Plenum Publishers; 2005;
  2. Meeran K, Hattersley A, Mould G, Bloom SR. Venepuncture causes rapid rise in plasma ACTH. Br J Clin Pract. 1993;47:246–247
  3. Wamboldt M, Laudenslager ML, Wamboldt FS, Kelsay K, Hewitt J. Adolescents with atopic disorders have an attenuated cortisol response to laboratory stress. J Allergy Clin Immunol. 2003;111:509–514
  4. Scheer FA, Van Paassen B, Van Montfrans GA, Fliers E, Van Someren EJ, Van Heerikhuize JJ, et al. Human basal cortisol levels are increased in hospital compared to home setting. Neurosci Lett. 2002;333:79–82
  5. Aardel E, Holm AC. Cortisol in saliva — reference ranges and relation to cortisol in serum. Eur J Clin Chem Clin Biochem. 1995;33:927–932
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  7. Calixto C, Martinez FE, Jorge SM, Moreira AC, Martinelli CE. Correlation between plasma and salivary cortisol levels in preterm infants. J Pediatr. 1995;140:116–118
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  9. Antonini SRR, Jorge SM, Moreira AC. Longitudinal evaluation of the development of salivary cortisol circadian rhythm in infancy. Clin Endocrinol. 2000;52:423–426
  10. Bettendorf M, Albers N, Bauer J, Heinrich UF, Linderkamp O, Maser-Gluth C. Longitudinal evaluation of salivary cortisol levels in full-term and preterm neonates. Horm Res. 1998;50:303–308
  11. Herrington J, Olomu IN, Geller SM. Salivary cortisol as indicators of pain in preterm infants. Clin Nurs Res. 2003;13:53–68
  12. Lupien SJ, Gaudreau S, Tchiteya BM, Maheu F, Sharma S, Nair NP, et al. Stress-induced declarative memory impairment in healthy elderly subjects: relationship to cortisol reactivity. J Clin Endocrinol Metab. 1997;82:2070–2075
  13. Stahl F, Dorner G. Responses of salivary cortisol levels to stress-situations. Endokrinologie. 1982;80:158–162
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  16. Krieger DT, Allen W, Rizzo F, Krieger HP. Characterization of the normal temporal pattern of plasma corticosteroid levels. J Clin Endocrinol Metab. 1971;32:266–284
  17. Scott S, Watterberg K. Effect of gestational age, postnatal age, and illness on plasma cortisol concentrations in premature infants. Pediatr Res. 1994;37:116–121
  18. Terrone DA, Smith LG, Wolf EJ, Uzbay LA, S.Sun RC. Neonatal effects and serum cortisol levels after multiple courses of maternal corticosteroids. Obstet Gynecol. 1997;90:819–823
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  21. de Weerth C, Zijl RH, Buitelaar JK. Development of cortisol circadian rhythm in infancy. Early Hum Dev. 2003;73:39–52

PII: S0378-3782(06)00131-9

doi: 10.1016/j.earlhumdev.2006.04.003

Early Human Development
Volume 83, Issue 1 , Pages 47-54 , January 2007

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