Early Human Development
Volume 85, Issue 11 , Pages 673-677, November 2009

Infant outcomes of assisted reproduction

  • Carrie Williams

      Affiliations

    • Tel.: +44 08451 555 000x3394; fax: +44 0207 3809064.
    • ,
  • Alastair Sutcliffe

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +44 0207 905 2367; fax: +44 20 7905 2834.

Institute of Child Health, UCL, General Paediatric & Adolescent Unit, 30 Guilford Road, London, WC1N 1EH, UK

Abstract 

Assisted reproductive technologies (ART) have become widely used in the treatment of subfertility over the last 30years. Currently 1.7% of all births in the UK occur after assisted conception. This review summarises work that has been undertaken to investigate health outcomes of these children and summarises areas where uncertainty continues to exist. Much of the adverse health outcomes of children born after ART are related to higher order birth; however evidence suggests adverse perinatal outcomes in singletons as well as twins and triplets. The cause of adverse health outcomes in ART conceived children is as yet unclear and studies investigating causal factors such as underlying subfertility are discussed.

Keywords: Reproductive techniques, Assisted, Fertilization in vitro, Infant, Follow-up studies

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PII: S0378-3782(09)00183-2

doi:10.1016/j.earlhumdev.2009.08.055

Early Human Development
Volume 85, Issue 11 , Pages 673-677, November 2009

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