Early Human Development
Volume 86, Issue 2 , Pages 69-70 , February 2010

Asymmetric dimethylarginine, an endogenous NO synthase inhibitor, in human breast milk

  • Hirokazu Tsukahara

      Affiliations

    • Department of Pediatrics, Fukui University Hospital, Fukui 910-1193, Japan
    • Corresponding Author InformationCorresponding author. Departments of Pediatrics, Fukui University Hospital, Fukui 910-1193, Japan. Tel.: +81 776 61 3111; fax: +81 776 61 8129.
  • ,
  • Hironori Nagasaka

      Affiliations

    • Department of Pediatrics, Chiba Children's Hospital, Chiba 266-0007, Japan

Received 16 December 2009 ,Revised 7 January 2010 ,Accepted 12 January 2010.

References 

  1. Leiper JM, Vallance P. The synthesis and metabolism of asymmetric dimethylarginine (ADMA). Eur J Clin Pharmacol. 2006;62:33–38
  2. Mittermayer F, Prusa AR, Pollak A, Wolzt M. Umbilical vein plasma concentrations of asymmetrical dimethylarginine are increased in male but not female neonates delivered preterm: a pilot study. Early Hum Dev. 2006;82:421–424
  3. Vida G, Sulyok E, Ertl T, Martens-Lobenhoffer J, Bode-Boger SM. Plasma asymmetric dimethylarginine concentration during the perinatal period. Neonatology. 2007;92:8–13
  4. Tsukahara H, Ohta N, Tokuriki S, Nishijima K, Kotsuji F, Kawakami H, et al. Determination of asymmetric dimethylarginine, an endogenous nitric oxide synthase inhibitor, in umbilical blood. Metabolism. 2008;57:215–220
  5. Akcay F, Aksoy H, Memisogullari R. Effect of breast-feeding on concentration of nitric oxide in breast milk. Ann Clin Biochem. 2002;39:68–69
  6. Ohta N, Tsukahara H, Ohshima Y, Nishii M, Ogawa Y, Sekine K, et al. Nitric oxide metabolites and adrenomedullin in human breast milk. Early Hum Dev. 2004;78:61–65

PII: S0378-3782(10)00023-X

doi: 10.1016/j.earlhumdev.2010.01.021

Early Human Development
Volume 86, Issue 2 , Pages 69-70 , February 2010