Early Human Development
Volume 86, Issue 3 , Pages 155-158 , March 2010

Monitoring of cerebral haemodynamics in newborn infants

  • K. Djien Liem

      Affiliations

    • Department of Neonatology, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 24 3613936; fax: +31 24 3619052.
    • ,
  • Gorm Greisen

      Affiliations

    • Department of Neonatology, Rigshospitalet, Blegdamvej 9, 2100 Copenhagen, Denmark
    • Tel.: +45 3545 1326; fax: +45 3545 5025.

References 

  1. Fawke J. Neurological outcomes following preterm birth. Semin Fetal Neonatal Med. 2007;12:374–382
  2. du Plessis AJ. Cerebrovascular injury in premature infants: current understanding and challenges for future prevention. Clin Perinatol. 2008;35:609–641
  3. Hambleton G, Wigglesworth JS. Origin of intraventricular haemorrhage in the preterm infant. Arch Dis Child. 1976;51:651–659
  4. O'Leary H, Gregas MC, Limperopoulos C, et al. Elevated cerebral pressure passivity is associated with prematurity-related intracranial hemorrhage. Pediatrics. 2009;124:302–309
  5. Volpe JJ. Intraventricular hemorrhage in the premature infant—current concepts.Part I.. Ann Neurol. 1989;25:3–11
  6. Volpe JJ. Intraventricular hemorrhage in the premature infant—current concepts. Part II.. Ann Neurol. 1989;25:109–116
  7. De Reuck JL. Cerebral angioarchitecture and perinatal brain lesions in premature and full-term infants. Acta Neurol Scand. 1984;70:391–395
  8. Blumenthal I. Periventricular leucomalacia: a review. Eur J Pediatr. 2004;163:435–442
  9. Marcus ML, Busija DW, Bischof CJ, Heistad DD. Methods for measurement of cerebral blood flow. Fed Proc. 1981;40:2306–2310
  10. Greisen G, Frederiksen PS, Mali J, Friis-Hansen B. Analysis of cranial 133-Xenon clearance in the newborn infant by the two-compartment model. Scand J Clin Lab Invest. 1984;44:239–250
  11. Wintermark M, Sesay M, Barbier E, et al. Comparative overview of brain perfusion imaging techniques. Stroke. 2005;36:e83–e99
  12. Edwards AD, Wyatt JS, Richardson C, Delpy DT, Cope M, Reynolds EO. Cotside measurement of cerebral blood flow in ill newborn infants by near infrared spectroscopy. Lancet. 1988;2:770–771
  13. Patel J, Marks K, Roberts I, Azzopardi D, Edwards AD. Measurement of cerebral blood flow in newborn infants using near infrared spectroscopy with indocyanine green. Pediatr Res. 1998;43:34–39
  14. Myers TF, Patrinos ME, Muraskas J, Caldwell CC, Lambert GH, Anderson CL. Dynamic trend monitoring of cerebral blood flow velocity in newborn infants. J Pediatr. 1987;110:611–616
  15. Greisen G. Analysis of cerebroarterial Doppler flow velocity waveforms in newborn infants: towards an index of cerebrovascular resistance. J Perinat Med. 1986;14:181–187
  16. Thoresen M, Haaland K, Steen PA. Cerebral Doppler and misrepresentation of flow changes. Arch Dis Child. 1994;71:F103–F106
  17. van Wijk MC, Klaessens JH, Hopman JC, Liem KD, Thijssen JM. Assessment of local changes of cerebral perfusion and blood concentration by ultrasound harmonic B-mode contrast measurement in piglet. Ultrasound Med Biol. 2003;29:1253–1260
  18. Greisen G. Is near-infrared spectroscopy living up to its promises?. Semin Fetal Neonatal Med. 2006;11:498–502
  19. Tsuji M, duPlessis A, Taylor G, Crocker R, Volpe JJ. Near infrared spectroscopy detects cerebral ischemia during hypotension in piglets. Pediatr Res. 1998;44:591–595
  20. Skov L, Pryds O, Greisen G. Estimating cerebral blood flow in newborn infants: comparison of near infrared spectroscopy and 133Xe clearance. Pediatr Res. 1991;30:570–573
  21. Chillon J, Baumbach G. Autoregulation: arterial and intracranial pressure. In:  Edvinsson L,  Krause D editor. Cerebral blood flow and metabolism. Philadelphia: Lippincott William & Wilkins; 2002;p. 395–412
  22. Greisen G. Autoregulation of cerebral blood flow in newborn babies. Early Hum Dev. 2005;81:423–428
  23. Panerai RB. Cerebral autoregulation: from models to clinical applications. Cardiovasc Eng. 2008;8:42–59
  24. Jayasinghe D, Gill AB, Levene MI. CBF reactivity in hypotensive and normotensive preterm infants. Pediatr Res. 2003;54:848–853
  25. Menke J, Michel E, Hillebrand S, von Twickel J, Jorch G. Cross-spectral analysis of cerebral autoregulation dynamics in high risk preterm infants during the perinatal period. Pediatr Res. 1997;42:690–699
  26. Pryds O, Greisen G, Lou H, Friis-Hansen B. Vasoparalysis associated with brain damage in asphyxiated term infants. J Pediatr. 1990;117:119–125
  27. Liem KD, Hopman JC, Oeseburg B, de Haan AF, Festen C, Kollée LA. Cerebral oxygenation and hemodynamics during induction of extracorporeal membrane oxygenation as investigated by near infrared spectrophotometry. Pediatrics. 1995;95:555–561
  28. De Smed D, Vanderhaegen J, Naulaers G, van Huffel S. New measurements for assessment of impaired cerebral autoregulation using near-infrared spectroscopy. Adv Exp Med Biol. 2009;645:273–278
  29. Soul JS, Hammer PE, Tsuji M, et al. Fluctuating pressure-passivity is common in the cerebral circulation of sick premature infants. Pediatr Res. 2007;61:467–473
  30. Wong FY, Leung TS, Austin T, et al. Impaired autoregulation in preterm infants identified by using spatially resolved spectroscopy. Pediatrics. 2008;121:e604–e611
  31. Pryds O, Greisen G, Skov LL, Friis-Hansen B. Carbon dioxide-related changes in cerebral blood volume and cerebral blood flow in mechanically ventilated preterm neonates: comparison of near infrared spectrophotometry and 133Xenon clearance. Pediatr Res. 1990;27:445–449
  32. Fenton AC, Woods KL, Evans DH, Levene MI. Cerebrovascular carbon dioxide reactivity and failure of autoregulation in preterm infants. Arch Dis Child. 1992;67:835–839
  33. Pryds O, Christensen NJ, Friis-Hansen B. Increased cerebral blood flow and plasma epinephrine in hypoglycemic, preterm neonates. Pediatrics. 1990;85:172–176
  34. Liem KD, Hopman JC, Oeseburg B, de Haan AF, Kollée LA. The effect of blood transfusion and haemodilution on cerebral oxygenation and haemodynamics in newborn infants investigated by near infrared spectrophotometry. Eur J Pediatr. 1997;156:305–310
  35. Tomita M. Significance of cerebral blood volume. In:  Tomita M,  Sawada H,  Naritomi D,  Heiss WD editor. Cerebral hyperemia and ischemia: from the standpoint of cerebral blood volume. Amsterdam: Elsevier Science Publishers. 1988;p. 3–31
  36. Wyatt JS, Cope M, Delpy DT, et al. Quantitation of cerebral blood volume in human infants by near-infrared spectroscopy. J Appl Physiol. 1990;68:1086–1091
  37. Brun NC, Greisen G. Cerebrovascular responses to carbon dioxide as detected by near-infrared spectrophotometry: comparison of three different measures. Pediatr Res. 1994;36:20–24
  38. Risberg J, Ancri D, Ingvar DH. Correlation between cerebral blood volume and cerebral blood flow in the cat. Exp Brain Res. 1969;8:321–326
  39. Grubb RL, Raichle ME, Eichling JO, Ter-Pogossian MM. The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time. Stroke. 1974;5:630–639
  40. Mchedlishvilli G. Maintenance of constant intracranial blood volume by veni-vasomotor reflex. In:  Tomita M,  Sawada H,  Naritomi D,  Heiss WD editor. Cerebral hyperemia and ischemia: from standpoint of cerebral blood volume. Amsterdam: Elsevier Science Publishers. 1988;p. 215–223
  41. Wyatt JS, Edwards AD, Cope M, et al. Response of cerebral blood volume to changes in arterial carbon dioxide tension in preterm and term infants. Pediatr Res. 1991;29:553–557
  42. Livera LN, Spencer SA, Thorniley MS, Wickramasinghe YA, Rolfe P. Effects of hypoxaemia and bradycardia on neonatal cerebral haemodynamics. Arch Dis Child. 1991;66:376–380
  43. Matsuda T, Okuyama K, Cho K, et al. Cerebral hemodynamics during the induction of antenatal periventricular leukomalacia by hemorrhagic hypotension in chronically instrumented fetal sheep. Am J Obstet Gynecol. 2006;194:1057–1063
  44. Toet MC, Lemmers PM, van Schelven LJ, van Bel F. Cerebral oxygenation and electrical activity after birth asphyxia: their relation to outcome. Pediatrics. 2006;117:333–339
  45. Wong FY, Barfield CP, Campbell L, Brodecky VA, Walker AM. Validation of cerebral venous oxygenation measured using near-infrared spectroscopy and partial jugular venous occlusion in the newborn lamb. J Cereb Blood Flow Metab. 2008;28:74–80
  46. Yoxall CW, Weindling AM, Dawani NH, Peart I. Measurement of cerebral venous oxyhemoglobin saturation in children by near-infrared spectroscopy and partial jugular venous occlusion. Pediatr Res. 1995;38:319–323
  47. Menssen J, Colier W, Hopman J, Liem D, de Korte C. A method to calculate arterial and venous saturation from near infrared spectroscopy (NIRS). Adv Exp Med Biol. 2009;645:135–140
  48. Matcher SJ, Kirkpatrick PJ, Nahid K, Cope M, Delpy DT. Absolute quantification methods in tissue near-infrared spectroscopy. Proc SPIE. 2005;2389:486–495
  49. McCormick PW, Stewart M, Goetting MG, Balakrishnan G. Regional cerebrovascular oxygen saturation measured by optical spectroscopy in humans. Stroke. 1991;22:596–602
  50. Brun NC, Moen A, Borch K, Saugstad OD, Greisen G. Near-infrared monitoring of cerebral tissue oxygen saturation and blood volume in newborn piglets. Am J Physiol. 1997;273:H682–H686
  51. Benni PB, Chen B, Dykes FD, et al. Validation of the CAS neonatal NIRS system by monitoring vv-ECMO patients: preliminary results. Adv Exp Med Biol. 2005;566:195–201
  52. Watzman HM, Kurth CD, Montenegro LM, Rome J, Steven JM, Nicolson SC. Arterial and venous contributions to near-infrared cerebral oximetry. Anesthesiology. 2000;93:947–953
  53. Dullenkopf A, Kolarova A, Schulz G, Frey B, Baenziger O, Weiss M. Reproducibility of cerebral oxygenation measurement in neonates and infants in the clinical setting using the NIRO 300 oximeter. Pediatr Crit Care Med. 2005;6:344–347
  54. Naulaers G, Meyns B, Miserez M, et al. Use of tissue oxygenation index and fractional tissue oxygen extraction as non-invasive parameters for cerebral oxygenation. A validation study in piglets. Neonatology. 2007;92:120–126

PII: S0378-3782(10)00040-X

doi: 10.1016/j.earlhumdev.2010.01.029

Early Human Development
Volume 86, Issue 3 , Pages 155-158 , March 2010

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