Early Human Development
Volume 86, Issue 6 , Pages 339-344, June 2010

Obstetric aspects of hypoxic ischemic encephalopathy

  • Sailesh Kumar

      Affiliations

    • Tel.: +44 208 3833998; fax: +44 208 3833507.
  • ,
  • Sara Paterson-Brown

      Affiliations

    • Corresponding Author InformationCorresponding author. Tel.: +44 208 3833998; fax: +44 208 3833507.

Queen Charlotte's and Chelsea Hospital, Imperial College London, Du Cane Road, London W12 0HS, United Kingdom

Abstract 

Hypoxic ischemic encephalopathy (HIE) describes neonatal encephalopathy that is caused by intrapartum asphyxia and it can result in the long term sequelae of cerebral palsy which is a major cause of disability. The incidence of cerebral palsy has not changed over the last few decades and the challenge to obstetricians remains how best to recognise those babies at risk of this intrapartum insult both before and during labour. Many associations and risk factors are unavoidable or unrecognisable, and others are fairly common and associated with poor predictive value. Intrapartum fetal heart monitoring remains the main focus of attention but how this is best achieved is still the subject of research. Computerised decision support systems built into fetal heart rate monitoring and non-invasive fetal ECG signal pick-up are currently being explored.

Keywords: Hypoxic ischemic encephalopathy, Neonatal encephalopathy, Intrapartum asphyxia, Cerebral palsy, Fetal heart monitoring

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S0378-3782(10)00107-6

doi:10.1016/j.earlhumdev.2010.05.009

Early Human Development
Volume 86, Issue 6 , Pages 339-344, June 2010