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Volume 86, Issue 6, Pages 339-344 (June 2010)


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Obstetric aspects of hypoxic ischemic encephalopathy

Sailesh Kumar1email address, Sara Paterson-BrownCorresponding Author Informationemail address

Abstract 

Hypoxic ischemic encephalopathy (HIE) describes neonatal encephalopathy that is caused by intrapartum asphyxia and it can result in the long term sequelae of cerebral palsy which is a major cause of disability. The incidence of cerebral palsy has not changed over the last few decades and the challenge to obstetricians remains how best to recognise those babies at risk of this intrapartum insult both before and during labour. Many associations and risk factors are unavoidable or unrecognisable, and others are fairly common and associated with poor predictive value. Intrapartum fetal heart monitoring remains the main focus of attention but how this is best achieved is still the subject of research. Computerised decision support systems built into fetal heart rate monitoring and non-invasive fetal ECG signal pick-up are currently being explored.

Queen Charlotte's and Chelsea Hospital, Imperial College London, Du Cane Road, London W12 0HS, United Kingdom

Corresponding Author InformationCorresponding author. Tel.: +44 208 3833998; fax: +44 208 3833507.

1 Tel.: +44 208 3833998; fax: +44 208 3833507.

PII: S0378-3782(10)00107-6

doi:10.1016/j.earlhumdev.2010.05.009


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